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Double-Layer Amniotic Membrane Transplantation in Limbal Stem Cell Deficiency With Severe Corneal Conjunctivalization

Majid Moshirfar, MD, and Mina Sitto, MD

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Majid Moshirfar, MD, presents a case of double-layer amniotic membrane transplantation in a patient with a history of chemical corneal injury resulting in limbal stem cell deficiency and severe corneal conjunctivalization. This results in the development of a dense central corneal scar with associated visual impairment. Although simple limbal epithelial transplantation was discussed as a potential management option, the patient ultimately elected to proceed with double-layer amniotic membrane transplantation.

Posted: 12/19/2025

Keywords:

Amniotic Membrane

•

Limbal Stem Cell Transplantation

•

conjunctivalization

•

Corneal Scar

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Double-Layer Amniotic Membrane Transplantation in Limbal Stem Cell Deficiency With Severe Corneal Conjunctivalization

Majid Moshirfar, MD, and Mina Sitto, MD

Majid Moshirfar, MD, presents a case of double-layer amniotic membrane transplantation in a patient with a history of chemical corneal injury resulting in limbal stem cell deficiency and severe corneal conjunctivalization. This results in the development of a dense central corneal scar with associated visual impairment. Although simple limbal epithelial transplantation was discussed as a potential management option, the patient ultimately elected to proceed with double-layer amniotic membrane transplantation.

Posted: 12/19/2025

Keywords:

Amniotic Membrane

•

Limbal Stem Cell Transplantation

•

conjunctivalization

•

Corneal Scar

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