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Transcleral Micropulse Laser Dynamically Alters Ciliary Muscle and Aqueous Outflow Pathways

Murray Johnstone, MD

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This video provides visually controlled, real time observation of the effects of a transcleral micropulse 810 nm laser. The laser pulses induce shortening of the longitudinal portion of the ciliary muscle. At low energies the laser may be primarily causing a contractile response with muscle relaxation after the initial contraction. At higher energy levels the ciliary body effect appears to be primarily thermal muscle bundle shrinkage and whitening with an absence of relaxation. Ciliary muscle shortening causes the scleral spur to move backward and inward placing tension on the trabecular meshwork tissues. The effect is similar to that of pilocarpine, a drug that improves aqueous outflow and reduces intraocular pressure. Many of the micropulse laser parameters have yet to be optimized but the findings suggest a long-term pilocarpine-like effect may be possible. [No sound]

Posted: 8/31/2017

Keywords:

aqueous outflow

•

Glaucoma

•

Micropulse Laser

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Transcleral Micropulse Laser Dynamically Alters Ciliary Muscle and Aqueous Outflow Pathways

Murray Johnstone, MD

This video provides visually controlled, real time observation of the effects of a transcleral micropulse 810 nm laser. The laser pulses induce shortening of the longitudinal portion of the ciliary muscle. At low energies the laser may be primarily causing a contractile response with muscle relaxation after the initial contraction. At higher energy levels the ciliary body effect appears to be primarily thermal muscle bundle shrinkage and whitening with an absence of relaxation. Ciliary muscle shortening causes the scleral spur to move backward and inward placing tension on the trabecular meshwork tissues. The effect is similar to that of pilocarpine, a drug that improves aqueous outflow and reduces intraocular pressure. Many of the micropulse laser parameters have yet to be optimized but the findings suggest a long-term pilocarpine-like effect may be possible. [No sound]

Posted: 8/31/2017

Keywords:

aqueous outflow

•

Glaucoma

•

Micropulse Laser

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Comments

Facundo Rodriguez

7 years ago

Excelent demonstration Dr Johnstone its very usefull to understand how this new technology works. Thanks for all your investigation

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