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Intrastromal corneal ring segments (ICRSs) offer several advantages over other refractive techniques to treat myopia and keratoconus. There is, however, a small but definite risk that infection may occur in the early or late postoperative period. Vishal Jhanji, MD; and Rasik B. Vajpayee, MS, FRCS(Edin), FRANZCO, present a case of late occurring microbial keratitis from resistant Staphylococcus epidermidis following ICRS implantation. The case is successfully managed with the double-bubble deep anterior lamellar keratoplasty technique.