A microscopic look at the biocompatibility of IOLs
Dr. Apple discusses the biocompatibility of polymers used in ocular implants, specifically polypropylene and PMMA IOLs. Various forms of cracking were observed on the surface of explanted polypropylene lenses which were thought to be caused by a change in the protein coating, superficial oxidation, or change in crystallinity of the polymer. Additionally, this superficial degradation was typically observed when the material was in close proximity to highly metabolic tissue within the posterior capsule, as seen with uvetis inflammation.
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